5-Fluorouracil factory 51-21-8 in China CAS NO.51-21-8

5-Fluorouracil factory 51-21-8 in China

Product name ：5-Fluorouracil

5-Fluoro Uracil is is an DNA/RNA synthesis inhibitor. It is used as a potent antitumor agent since it interrupts nucleotide synthetic by inhibiting thymidylate synthase.

Synonyms

5-Fluoro-2,4(1H,3H)-pyrimidinedione

5-Fluoro-2,4-pyrimidinedione

5-Fluoropyrimidine-2,4-dione

CAS No. 51-21-8

EINECS 200-085-6

Molecular formula C4H3FN2O2

Molecular weight 130.08

Appearance

White to off- white crystalline powder

Melting point  278-286 ºC

Boiling point  401.4 °C at 760 mmHg

Assay  99%mmin

Packing

25Kg/drum or as required

Application

Used for digestive system cancer, head and neck cancer, gynecological cancer, lung cancer, liver cancer, bladder cancer and skin cancer treatment

1.  Rich experience in loading a great amount of containers in Chinese sea port;
2.  Fast shipment by well-reputed shipping line;
3.  Packaging with pallets according to buyers’ special request;
4.  Cargoes together with container sales service available;
5.  Rich experience in Korea,India &Europe export.

Synchem is dedicated to custom synthesis and manufacturing services for small molecules. We specialize in advanced fluorinating techno-logy, asymmetrical catalysis technology, and highly effective organic-metal catalysis technology.

5-Fluorouracil factory 51-21-8 in China

Product Description:

Fluorouracil has been given systemically for anal, breast,colorectal,oesophageal,stomach, pancreatic and skin cancers (especially head and neck cancers).It has also been given topically for actinic keratoses and Bowen's disease.

Function:

5-Fluorouracil is a potent antitumor agent that affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. It is metabolized to ribonucleotides and deoxyribonucleotides, which can be incorporated into RNA and DNA. Treatment of cells with 5-FU leads to an accumulation of cells in S-phase and has been shown to induce p53 dependent apoptosis.

Application:
1. It is used for biochemical studies and antitumor drugs.

2. It is the anti tumor drug, also used for synthesis of flucytosine. 5- fluorouracil can be used in the study of rice in the biochemical studies, ear differentiation, genetic metabolic measurement, plant growth development research.

3. It is used for the digestive system cancer, head and neck cancer, gynecological cancer, lung cancer, liver cancer, treatment of bladder cancer and skin cancer.

4. Antimetabolite antitumor drugs.

5. Anti tumor drugs. There is a certain effect on a variety of tumors such as digestive tract cancer, breast cancer, ovarian cancer, chorionic epithelial cancer, cervical cancer, hepatocellular carcinoma, bladder cancer, skin cancer (topical), leukoplakia (topical) etc. Adverse reactions mainly are bone marrow transplantation, digestive tract reaction, serious person can have diarrhea, local injection site phlebitis, a few of which have nervous system reactions such as cerebellar degeneration and ataxia. The course of medication should strictly check the blood.

Why Choose China Synchem  

1. Quality

Our products meet MSDS safe standard and we have ISO and other certificate so yan can get high quality products from our company.

2. Price

We are the company which is the joint of trade and industry so we cao provide the competitive price and high quality product.

3. Packing

We can do according to the customers' request.

4. Transport

The products can be transported  by Courier, by air or by sea

5. Service

We offer specialized logistic service including export declaration,customs clearance and every detail during shipment,this makes us able to offer you one-stop service from the order to the products transported to your hand.