5-Fluorouracil with immediately delivery from good supplier /Hot sale 51-21-8 CAS NO.51-21-8

5-Fluorouracil with immediately delivery from good supplier /Hot sale 51-21-8

Product name ：5-Fluorouracil

5-Fluoro Uracil is is an DNA/RNA synthesis inhibitor. It is used as a potent antitumor agent since it interrupts nucleotide synthetic by inhibiting thymidylate synthase.

Synonyms

5-Fluoro-2,4(1H,3H)-pyrimidinedione

5-Fluoro-2,4-pyrimidinedione

5-Fluoropyrimidine-2,4-dione

CAS No. 51-21-8

EINECS 200-085-6

Molecular formula C4H3FN2O2

Molecular weight 130.08

Appearance

White to off- white crystalline powder

Melting point  278-286 ºC

Boiling point  401.4 °C at 760 mmHg

Assay  99%mmin

Packing

25Kg/drum or as required

Application

Used for digestive system cancer, head and neck cancer, gynecological cancer, lung cancer, liver cancer, bladder cancer and skin cancer treatment

1.  Rich experience in loading a great amount of containers in Chinese sea port;
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4.  Cargoes together with container sales service available;
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Synchem is dedicated to custom synthesis and manufacturing services for small molecules. We specialize in advanced fluorinating techno-logy, asymmetrical catalysis technology, and highly effective organic-metal catalysis technology.

5-Fluorouracil with immediately delivery from good supplier /Hot sale 51-21-8

Product Description:

Fluorouracil has been given systemically for anal, breast,colorectal,oesophageal,stomach, pancreatic and skin cancers (especially head and neck cancers).It has also been given topically for actinic keratoses and Bowen's disease.

Function:

5-Fluorouracil is a potent antitumor agent that affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. It is metabolized to ribonucleotides and deoxyribonucleotides, which can be incorporated into RNA and DNA. Treatment of cells with 5-FU leads to an accumulation of cells in S-phase and has been shown to induce p53 dependent apoptosis.

Application:
1. It is used for biochemical studies and antitumor drugs.

2. It is the anti tumor drug, also used for synthesis of flucytosine. 5- fluorouracil can be used in the study of rice in the biochemical studies, ear differentiation, genetic metabolic measurement, plant growth development research.

3. It is used for the digestive system cancer, head and neck cancer, gynecological cancer, lung cancer, liver cancer, treatment of bladder cancer and skin cancer.

4. Antimetabolite antitumor drugs.

5. Anti tumor drugs. There is a certain effect on a variety of tumors such as digestive tract cancer, breast cancer, ovarian cancer, chorionic epithelial cancer, cervical cancer, hepatocellular carcinoma, bladder cancer, skin cancer (topical), leukoplakia (topical) etc. Adverse reactions mainly are bone marrow transplantation, digestive tract reaction, serious person can have diarrhea, local injection site phlebitis, a few of which have nervous system reactions such as cerebellar degeneration and ataxia. The course of medication should strictly check the blood.

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